2026
Proximity biotinylation at the host-Shigella interface reveals UFMylation as an antibacterial pathway. López-Jiménez AT, Théry F, Wright K, Painter H, Hoffmeister ST, Jarche L, Benjamin J, van der Heden van Noort GJ, Brokatzky D, Gomes MC, Miles SL, Lobato-Márquez D, Frickel EM, Rohde J, Pruneda JN, Impens F, Mostowy S. (Accepted)
2025
Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei. Miles SL, Santillo DM, Painter H, Wright K, Torraca V, López-Jiménez AT, Virgo M, Matanza XM, Clements A, Jenkins C, Baker S, Baker KS, Cisneros D, Puhar A, Sancho-Shimizu V, Holt KE, Mostowy S. Nat Commun 16, 9005 (2025). DOI: 10.1038/s41467-025-64057-y
High-content high-resolution microscopy and deep learning assisted analysis reveals host and bacterial heterogeneity during Shigella infection. López-Jiménez AT, Brokatzky D, Pillay K, Williams T, Özbaykal Güler G, Mostowy S. eLife 13:RP97495. (2025) 583762 DOI: 10.7554/eLife.97495.3
2024
The great escape: a Shigella effector unlocks the septin cage López-Jiménez AT, Özbaykal-Güler G, Mostowy S. Nat Commun 15, 4104 (2024). DOI: 10.1038/s41467-024-48208-1
2023
2021
Interplay between septins and ubiquitin-mediated xenophagy during Shigella entrapment. Lobato-Márquez D, Conesa JJ, López-Jiménez AT, Divine ME, Pruneda JN, Mostowy S. Autophagy Rep. 2(1):2213541. (2023) DOI: 10.1080/27694127.2023.2213541
Septins and K63 ubiquitin chains are present in separate bacterial microdomains during autophagy of entrapped Shigella. Lobato-Márquez D, Conesa JJ, López-Jiménez AT, Divine ME, Pruneda JN, Mostowy S. J Cell Sci. Apr 1;136(7):jcs261139 (2023) DOI: 10.1242/jcs.261139
Acquisition of a large virulence plasmid (pINV) promoted temperature-dependent virulence and global dispersal of O96:H19 enteroinvasive Escherichia coli. Miles SL, Torraca V, Dyson ZA, López-Jiménez AT, Foster-Nyarko E, Lobato-Márquez D, Jenkins C, Holt KE, Mostowy S. mBio 14(4):e0088223 (2023) DOI: 10.1128/mbio.00882-23
An automated microscopy workflow to study Shigella-neutrophil interactions and antibiotic efficacy in vivo. Lensen A, Gomes MC, López-Jiménez AT, Mostowy S. Dis Model Mech 16(6):dmm049908 (2023) DOI: 10.1242/dmm.049908
Emerging technologies and infection models in cellular microbiology. López-Jiménez AT, Mostowy S. Nat Commun (2021). DOI: 10.1038/s41467-021-26641-w
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Klionsky DJ, et al. [including López-Jiménez - AT]. Autophagy (2021). DOI: 10.1080/15548627.2020.1797280
2019
The developmental cycle of Dictyostelium discoideum ensures curing of a mycobacterial infection at both cell-autonomous level and by collaborative exclusion. López-Jiménez AT, Hagedorn M, Delincé MJ, McKinney JD, Soldati T. bioRxiv 586263. DOI: 10.1101/586263
2018
The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection. López-Jiménez AT, Cardenal-Muñoz E, Leuba F, Gerstenmaier L, Barisch C, Hagedorn M, King JS, Soldati T. PLoS Pathog. 13(14) (2018). DOI: 10.1371/journal.ppat.1007501
Localization of all four ZnT zinc transporters in Dictyostelium and impact of ZntA and B knockout on bacteria killing. Barisch C, Kalinina V, Lefrançois LH, Appiah J, López-Jiménez AT, Soldati T. Journal of Cell Science 131(23), (2018) DOI: 10.1242/jcs.222000
When Dicty met Myco, a (not so) romantic history about one amoeba and its intracellular pathogen. Cardenal-Munoz E, Barisch C, Lefrançois LH, López-Jiménez AT and Soldati T. Frontiers in Cellular and Infection Microbiology 7:529 (2018).
Eat prey, live: Dictyostelium discoideum as a model for cell-autonomous defenses. Dunn JD, Bosmani C, Barisch C, Raykov L, Lefrançois LH, Cardenal-Muñoz E, López-Jiménez AT and Soldati T. Frontiers in Immunology 8:1906 (2018). DOI: 10.3389/fimmu.2017.01906
2017
Mycobacterium marinum antagonistically induces an autophagic response while repressing autophagic flux in a TORC-1 and ESX-1 dependent manner. Cardenal-Muñoz E, Arafah S, López-Jiménez AT, Kicka S, Falaise A, Bach F, Schaad O, King JS, Hagedorn M, Soldati T. PLoS Pathog 13(4) (2017). DOI: 10.1371/journal.ppat.1006344
2016
A microfuidic cell-trapping device for single-cell tracking of host-microbe interactions. Delincé A, Bureau JB, López-Jiménez AT, Cosson P, Soldati T, McKinney JD. Lab Chip 16(17):3276-85 (2016). DOI: 10.1039/c6lc00649c
2015
Living imaging of Mycobacterium marinum infection in Dictyostelium discoideum. Barisch C*, López-Jiménez AT*, Soldati T. Methods Mol Biol. 1285:369-85 (2015). DOI: 10.1007/978-1-4939-2450-9 23